Lead has no known beneficial function in human metabolism.
The leading sources of human lead exposure are the following:
- Lead-containing paint
- Food stored in lead can liners
- Food stored in ceramic jars
- Contaminated water (pipes cast in lead or soldered using lead solder)
In addition to direct ingestion of lead, studies also suggest that lead can be absorbed through the skin. Once lead is in the human body, it has the ability of cross the blood brain barrier.
Children absorb lead up to 8-times more efficiently than adults. 1
Lead can be excreted from the body through feces or urine. 2
The toxicological effect of lead can be reviewed at the website Agency for Toxic Substances and Disease Registry.
Detoxification Strategies for Lead Poisoning
Chelation therapy is a medical procedure that involves the administration of chelating agents to remove heavy metals from the body.
Chelation therapy is used as a treatment for metal poisoning, including acute metal poisoning by:
The chelating agent used for detoxification of metal poisoning is administered either:
Chelation therapy is performed under the supervision of a licensed health care professional. Patients should seek the advise and counsel from a licensed health care professional when considering chelation therapies. Patients can contact the The American College for Advancement in Medicine (ACAM) for a U.S. national directory of physicians that practice and are licensed as chelation therapists.
There are 4 common chelating agents that are used (in the United States) for chelating lead poisoning:
|Dimercaprol (British anti-Lewisite; BAL)||Intravenous||lead poisoning|
|Dimercaptosuccinic acid (DMSA)||Oral||lead poisoning|
|Ethylenediamine tetraacetic acid (calcium disodium versante) (CaNa2-EDTA)||Intravenous||lead poisoning|
Two other candidates for chelating lead include:
- Polygamma-glutamic acid-coated superparamagnetic nanoparticles. These nanoparticles have been shown to have a high removal level of lead from the gastrointestinal fluid at 147.71 mg per gram. 3
- Magnetic chitosan/graphene oxide composites. A 2013 study found that magnetic chitosan/graphene oxide composites had highly selective adsorption of lead ions at 76.94 mg per gram. 4
Natural Substances (Nutraceuticals, Foods and Herbs) that Detoxify and Ameliorate the Effects of Lead Poisoning
In addition to the more aggressive chelation therapies administered and supervised by a licensed health care professional, there are certain natural substances that have been studied for their ability to either detoxify lead poisoning and/or ameliorate the toxic effects of lead poisoning.
The Table below lists these various natural substances and their scientific references:
Nutraceuticals, Foods and Herbs that Detoxify and Ameliorate the Effects of Lead Poisoning
Category Nutraceuticals/Foods/Herbs References
Algae Spirulina 1 2
Amino acids N-Acetyl-Cystiene (NAC) 3 4 5
Taurine 6 7 8 9
Carbohydrates Modified Citrus Pectin 10
Foods Poly(gamma-glutamic acid) from Japanese Natto 11
Herbs Ashwagandha 13
Coriander 14 15
Green Tea 16
Hormones Melatonin 17 18 19
Lipids Fish Oil (DHA and EPA) 20
Minerals Calcium 21
Polyphenols Curcumin 24 25
Vitamins Alpha Lipoic Acid 27
Vitamin B1 28
Vitamin C 29 30 31 32
Print This Post