GABA: Enhancing this Important Neurotransmitter

Gamma-Aminobutyric acid (γ-Aminobutyric acid) or GABA, is the chief inhibitory neurotransmitter in the mammalian central nervous system. It plays the principal role in reducing neuronal excitability throughout the nervous system. The features of the GABA system are characterized in the following Table: GABA Synthesis GABA is synthesized from glutamate using the enzyme L-glutamic acid decarboxylase

Preventing Brain Atrophy and Cognitive Decline with Omega-3 Fatty Acids and B-Complex Vitamins

Brain Atrophy Brain atrophy, or brain shrinkage, is the opposite of neurogenesis. Brain atrophy describes a loss of neurons and the connections between them. Figure 1.  Normal brain versus Atrophic brain  (Source) Brain atrophy can be categorized as either general or focal. With general brain atrophy, all of the brain shrinks. With focal brain atrophy,

A Multiprong Approach to Mild Cognitive Impairment – Prong One: Nutrients that Support Brain Function

According to the Mayo Clinic, Mild Cognitive Impairment (MCI) is defined as: “Mild cognitive impairment (MCI) is an intermediate stage between the expected cognitive decline of normal aging and the more serious decline of dementia. It can involve problems with memory, language, thinking and judgment that are greater than normal age-related changes. If you have

Balancing Your Neurotransmitter Systems Naturally

A balanced and healthy nervous system requires a sufficient level of neurotransmitters.  There are a number of neurotransmitters that have been identified and are typically classified as: Amino acids Monoamines Peptides Another classification of neurotransmitters is whether they are inhibitory or stimulatory.  For purposes of this article, four main neurotransmitters are examined: Stimulatory Acetylcholine Dopamine

Pyroglutamate Improves Blood Circulation to the Brain

Pyroglutamate (also known as L-pyroglutamic acid, PCA, 5-oxoproline, or pidolic acid) is an amino acid found in certain fruits, vegetables, meat and dairy products. In individuals, this amino acid tends to be primarily located in the: brain blood cerebrospinal fluid making it important for a properly functioning nervous system and brain activity. Studies have found

Centella asiatica (Gotu Kola): Considered a “Miracle Elixir of Life” by Traditional Chinese Medicine*

Introduction of Centella asiatica Centella asiatica is a small perennial plant of the family Mackinlayaceae or subfamily Mackinlayoideae of family Apiaceae, and is native to wetlands in Asia.  It is commonly known as Gotu Kola. Centella asiatica (CA) has been used extensively in Asia and is considered a very important medicinal herb in that region

Psychobiotics: Examining the Positive Effects of Probiotics on Mood Disorders and Stress

Human Microbiota The human microbiota consists of an aggregate of microorganisms that reside on or within a number of tissues and biofluids, including the skin, mammary glands, placenta, seminal fluid, uterus, ovarian follicles, lung, saliva, oral mucosa, conjunctiva, and gastrointestinal tracts. These microbiota include bacteria, fungi, and archaea.  For many years it has been estimated

Ammonia detoxification

Ammonia is manufactured as a by-product of “depleted” amino acids and endogenous proteins. The leftover nitrogen atoms from depleted amino acids combine with hydrogen to form Ammonia. Ammonia is combined with endogenous carbon dioxide and excreted from the body via the urine as urea. Ammonium ions are a toxic waste product of the metabolism in