Dietary Supplements that Show Promise for Cancer Prevention and Adjuvant Treatment*


The link between cancer and diet has been extensively studied.  In fact, major medical institutions recognize diet and nutritional supplements as a means to reduce the risk of cancer.  There are a number of websites that address this important issue:

Cancer is the second most leading cause of death in the United States.  1 

Of all the cancer deaths (at least in the U.S.), there are primarily two causes:  2

  • Genetic defects                        5-10%
  • Environment and lifestyle       90-95%

The lifestyle factors include:  3

  • Alcohol
  • Cigarette smoking
  • Diet (fried foods, red meat)
  • Environmental pollutants
  • Infections
  • Obesity
  • Stress
  • Sun exposure

Evidence suggests that of all the cancer deaths, 30–35% are linked to diet.  4

There are certain natural nutrients and hormones that have been studied for their effective mechanisms of action that may benefit the cancer patient and/or prevent cancer tumor genesis. 

An excellent paper is published on the Life Extension website entitled “Cancer Adjuvant Therapy”.  This paper illustrates an alphabetical list that follows provides quick guidelines for structuring a program, highlighting major nutrients in the prevention and treatment of cancer.

The Table below (from the paper “Cancer Adjuvant Therapy”) list those natural nutrients and hormone that have been researched for their ability to act as promising therapies for the prevention and treatment of certain cancers.  The references for each nutrient and hormone is one of many that exist, and is a starting point for further research.

Basic dietary supplements and suggested doses for cancer prevention and adjuvant treatment

NutrientReferencePreventive DoseCancer Adjuvant Dose
Apigenin110 – 25 mg daily20 – 50 mg daily
Astaxanthin22 – 4 mg daily6 – 12 mg daily
Astragalus3500 mg daily2000 – 4000 mg daily
Blueberry4180 – 450 mg daily900 – 1800 mg daily
Chrysin5500 mg daily1000-2000 mg daily
Curcumin6400 mg daily of a  BCM-95® extract with food800-3600 mg daily of a BCM-95® extract with food
Coenzyme Q107100 mg daily with food200-400 mg daily with food
Green Coffee Extract(standardized to 50% chlorogenic acid)8400 mg three times daily, before meals400 mg three times daily, before meals
EPA-DHA fatty acids92000 – 4000 mg daily of fish oil concentrate supplying 700 – 1400 mg EPA and 500 – 1000mg DHA with food4000 – 8000 mg daily of fish oil concentrate supplying up to 2800 mg EPA and 2000 mg DHA with food
Garlic10600 mg daily with food1200 – 4800 mg daily with food
Gamma Tocopherol11200 – 250 mg daily with food400 – 1000 mg daily with food
GLA (gamma-linolenic acid)12300 mg daily with food700 – 900 mg daily with food
Grape Seed Extract13100 mg daily300 mg daily
Green Tea Extract 14300 – 350 mg daily of EGCGUp to 3000 mg daily of EGCG
Cruciferous vegetable concentrate151 tbsp daily1 – 4 tbsp daily
Indole 3 Carbinol(I3C)1680 – 160 mg daily200 – 600 mg daily
Lignans1725 – 50 mg daily75 – 125 mg daily
Lipoic acid (Sodium R-lipoate)18240 – 480 mg daily on an empty stomach600 – 1200 mg daily on an empty stomach
Lycopene1910 mg daily with food15 – 45 mg daily with food
Melatonin20300 mcg-3 mg before bed10 – 50 mg between 8 – 10pm
Panax ginseng21100 mg daily of standardized to contain 4-7% ginsenosides200 – 600 mg daily of standardized to contain 4-7% ginsenosides
Pomegranate2280 – 120 mg daily of punicalagins280 – 375 mg daily of punicalagins
Proteolytic Enzymes231 – 2 pills daily on an empty stomach of a formula containing pancreatin, papain, trypsin, and chymotrypsin2 – 10 pills, 3 times daily on an empty stomach of a formula containing pancreatin, papain, trypsin, and chymotrypsin
PSK (Coriolusversicolor)24600 – 1200 mg daily of a 40% polysaccharide extract3000 mg daily of a 40% polysaccharide extract
Pterostilbene250.25-3 mg daily1 – 3 mg daily
Quercetin26500 mg daily1000 – 3000 mg daily
Reishi27980 mg daily of standardized to contain 13.5% polysaccharides and 6% triterpenes980 – 3000 mg daily of standardized to contain 13.5% polysaccharides and 6% triterpenes
Selenium28200 mcg daily with food200 – 600 mcg daily with food
Silibinin29225 mg daily225 – 450 mg daily
Sulforaphane30400 – 800 mg daily (broccoli extract)400 – 1600 mg daily (broccoli extract)
Vitamin C311000 – 3000 mg daily4 – 12 g daily
Vitamin D3322000 – 10 000 IU daily with food, based on individual blood testing. Optimal blood levels of vitamin D are 50 – 80 ng/ml.2000 – 10 000 IU daily with food, based on individual blood testing. Optimal blood levels of vitamin D are 50 – 80 ng/ml.
Source: Life Extension Cancer Adjuvant Therapy

*Disclaimer and Safety Information

BioFoundations can assume no responsibility for outcome, apart from a self-assigned duty to stay abreast of the most promising of therapies and to share the data with customers. No warranties (expressed or implied) accompany the material; neither is the information intended to replace medical advice. As always, each reader is urged to consult professional help for medical problems, especially those involving cancer.

This information (and any accompanying material) is not intended to replace the attention or advice of a physician or other qualified health care professional. Anyone who wishes to embark on any dietary, drug, exercise, or other lifestyle change intended to prevent or treat a specific disease or condition should first consult with and seek clearance from a physician or other qualified health care professional. Pregnant women in particular should seek the advice of a physician before using any protocol listed on this website.

The protocols described on this website are for adults only, unless otherwise specified. Product labels may contain important safety information and the most recent product information provided by the product manufacturers should be carefully reviewed prior to use to verify the dose, administration, and contraindications. National, state, and local laws may vary regarding the use and application of many of the treatments discussed. The reader assumes the risk of any injuries. The authors and publishers, their affiliates and assigns are not liable for any injury and/or damage to persons arising from this protocol and expressly disclaim responsibility for any adverse effects resulting from the use of the information contained herein.








Coenzyme Q10

Green Coffee Extract(standardized to 50% chlorogenic acid)

EPA-DHA fatty acids


Gamma Tocopherol

GLA (gamma-linolenic acid)

Grape Seed Extract

Green Tea Extract

Cruciferous vegetable concentrate

Indole 3 Carbinol(I3C)


Lipoic acid (Sodium R-lipoate)



Panax ginseng


Proteolytic Enzymes

PSK (Coriolusversicolor)







Vitamin C

Vitamin D3

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