Curry Leaf is Not the Same as Curry

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The curry tree (Murraya koenigii) is a tropical to sub-tropical tree in the family Rutaceae (the rue family, which includes rue, citrus, and satinwood), which is native to India and Sri Lanka.

curryleaf2

Its leaves are used in many dishes in India and neighboring countries. Often used in curries, the leaves are generally called by the name ‘curry leaves’.

Below is a list of the active compounds of Curry Leaf:

Curry Leaf Compounds

Curry leaf 
CategoryCompound
Alkaloids
2-methoxy-3-methyl-carbazole
girinimbine, koenimbine
Indicolactone
isomahanine
Mahanimbine
mahanine
Oleoresin
8,10‘-[3,3‘,11,11‘-tetrahydro-9,9‘-dihydroxy-3,3‘,5,8‘-tetramethyl-3,3‘-bis(4-methyl-3-pentenyl)]bipyrano[3,2-a]carbazole
O-methylmurrayamine A
O-methylmahanine
isomahanine
bismahanine
bispyrayafoline
Sesqui­terpene hydro­carbons
limonene
α‑selinene
β‑bisa­bolene
β‑cadinene
β‑caryo­phyllene
β‑elemene
β‑gurjun­ene
β‑phel­landrene
β‑thujene
β‑trans‑ocimene

The Table below lists the recognized and researched studies on the health benefits of Curry Leaf:

Curry Leaf Health Benefits

Curry Leaf   
BioSystemCategoryBenefitReference
Detoxification
Apoptosis
A 2011 study of girinimbine, a carbazole alkaloid isolated from this plant, found that it inhibited the growth and induced apoptosis in human hepatocellular carcinoma, HepG2 cells in vitro.1
Immune System
Breast cancer
Efficacy of koenimbin, isolated from Murraya koenigii (L) Spreng, in the inhibition of MCF7 breast cancer cells and to target MCF7 breast cancer stem cells through apoptosis in vitro.2
Anti-Inflammatory
The petroleum ether, chloroform and
ethanol extracts of Murraya koenigii were screened at dose of (250mg/kg) for anti inflammatory
activity by using acute carrageen induced paw oedema method and yeast induces hyperpyrexia
method respectively. The ethanolic extract shows significant effects in anti-inflammatory activity.
3
Metabolism
Antioxidant
Oleoresin of curry leaves (Murraya koenigii Spreng.), obtained using acetone, was evaluated for its antioxidant activity . The oleoresin showed maximum activity of 83.2% at 100 ppm 4
Neurological
Memory
Murraya koenigii (curry leaf extract) has been shown to improve memory in animal models, perhaps by reducing cholinesterase activity5
Acetylcholinesterase Inhibitor
The AChE inhibitory activity of a carbazole alkaloid isolated from Murraya koenigii6
Dementia
Alkaloidal extract from M. koenigii leaves (MKA) to be a useful remedy in the management of Alzheimer's disease and dementia.7


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