Glucose is a simple monosaccharide. It is one of the three dietary monosaccharides, (the other two being fructose and galactose), that is directly absorbed into the bloodstream during the digestion process.
Our body’s primary source of energy is glucose, which is used by the cells via aerobic respiration or anaerobic respiration. When glucose is properly utilized, our cells produce energy efficiently. As cellular sensitivity to insulin diminishes, excess glucose accumulates in our bloodstream.
Excess blood glucose creates an environment in which oxidative and inflammatory fires chronically erupt. Excess glucose in the bloodstream also initiates the glycation process of glucose molecules bonding with protein or lipid molecules that produce nonfunctioning and deformed molecules known as advanced glycation end products (AGE’s). These damaging glycation reactions fuel the fires of chronic inflammation and incite the production of destructive free radicals.
Excess glucose not used for energy production converts to triglycerides that are either stored as unwanted body fat or accumulate in the blood where they contribute to the formation of atherosclerotic plaque.
There exists scientific data that shows that by taking the proper compounds before meals, the surge of glucose into the bloodstream and the subsequent insulin spike can be mitigated.
Blood Glucose Levels
- Fasting glucose ranges should be 70-85 mg/dL
- Above 85 mg/dL are at increased risk of heart attack
- Do not allow after meal glucose levels to spike higher than 40 mg/dL
- 85 md/dL plus 40 mg/dL equals 125 mg/dL (Maximum limit of post pandrial glucose level)
- Never exceed 140 mg/dL post pandrial glucose level
Compounds that are thought to control Blood Glucose Levels:
- Benfotiamine 
- Alpha Lipoic Acid
- Niacinamide 
- Pinitol (D-Chiro-Inositol) 
- Biotin 
- L-Glutamine 
- Chromium (Polynicotinate form) 
- Cinnamon 
- Berberine 
- Touchi Extract
- Banaba Leaf 
- Mulberry Extract (Moranoline (Morus Alba leaf)) 
- Gymnema Sylvestre 
- American Ginseng 
- Bitter Melon 
- White Kidney Bean extract (phaseolus vulgaris) 
- Rutin 
- Coffee Berry Extract (chlorogenic acid and caffeic acid)
References: Hammes, H. P., et al. Benfotiamine blocks three major pathways of hyperglycemic damage and prevents experimental diabetic retinopathy. Nature Medicine. 9(3):294-299, 2003.  Obrosova, I. G., et al. [Hypoglycemic effect of nicotinamide in diabetes mellitus.] Farmakol Toksikol. 50(2):113-115, 1987.  Bates, S. H., et al. Insulin-like effect of pinitol. British Journal of Pharmacology. 130:1944-1948, 2000.  Koutsikos, D., et al. Oral glucose tolerance test after high-dose i.v. biotin administration in normoglucemic hemodialysis patients. Ren Fail. 18(1):131-137, 1996.  Opara, E. C., et al. L-glutamine supplementation of a high fat diet reduces body weight and attenuates hyperglycemia and hyperinsulinemia in C57BL/6J mice. Journal of Nutrition. 126(1):273-279, 1996.  Preuss, H. G., et al. Chromium update: examining recent literature 1997-1998. Curr Opin Clin Nutr Metab Care. 1:509-512, 1998. Hlebowicz, J., et al. Effect of cinnamon on postprandial blood glucose, gastric emptying, and satiety in healthy subjects. American Journal of Clinical Nutrition. 85(6):1552-1556, 2007.  Zhou, L., et al. Berberine stimulates glucose transport through a mechanism distinct from insulin. Metabolism. 56(3):405-412, 2007.  Klein, G., et al. Antidiabetes and anti-obesity activity of Lagerstroemia speciosa. Evid Based Complement Alternat Med. 4(4):401-407, 2007  Miyahara, C., et al. Inhibitory effects of mulberry leaf extract on postprandial hyperglycemia in normal rats. J Nutr Sci Vitaminol (Tokyo). 50(3):161-164, 2004.  Shimizu, K., et al. Suppression of glucose absorption by some fractions extracted from Gymnema sylvestre leaves. J Vet Med Sci. 59(4):245-251, 1997.  Vuksan, V., et al. American ginseng (Panax quinquefolius L.) attenuates postprandial glycemia in a time-dependent but not dose-dependent manner in healthy individuals. American Journal of Clinical Nutrition. 73(4):753-758, 2001.  Chaturvedi, P., et al. Momordica charantia maintains normal glucose levels and lipid profiles and prevents oxidative stress in diabetic rats subjected to chronic sucrose load. J Med Food.13(3):520-527, 2010.  Tormo, M. A., et al. Hypoglycaemic and anorexigenic activities of an alpha-amylase inhibitor from white kidney beans (Phaseolus vulgaris) in Wistar rats. Br J Nutr. 92(5):785-790, 2004.  Stanley Mainzen Prince, P., et al. Rutin improves glucose homeostasis in streptozotocin diabetic tissues by altering glycolytic and gluconeogenic enzymes. J Biochem Mol Toxicol. 20(2):96-102, 2006.
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